15. Which of the following types of drugs will have maximum oral bioavailability? A. Chemically unstable drugs B. Drugs that are P-glycoprotein substrates C. Drugs with high first-pass metabolism D. Highly hydrophilic drugs E. Largely hydrophobic, yet soluble in aqueous solutions

Biology

Question
15. Which of the following types of drugs will have maximum oral bioavailability?
A. Chemically unstable drugs
B. Drugs that are P-glycoprotein substrates
C. Drugs with high first-pass metabolism
D. Highly hydrophilic drugs
E. Largely hydrophobic, yet soluble in aqueous solutions
Answer

E. Largely hydrophobic, yet soluble in aqueous solutions

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Oral bioavailability is the amount of a drug that is absorbed into the bloodstream after being taken orally. Drugs that are highly hydrophobic,...
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