Question
15. Which of the following types of drugs will have maximum oral bioavailability?
A. Chemically unstable drugs
B. Drugs that are P-glycoprotein substrates
C. Drugs with high first-pass metabolism
D. Highly hydrophilic drugs
E. Largely hydrophobic, yet soluble in aqueous solutions
Answer
E. Largely hydrophobic, yet soluble in aqueous solutions